“Heteroatom-tagged” quantification of proteins via ICP-MS

Agilent 8800 Triple Quadrupole ICP-MS: Understanding oxygen reaction mode in ICP-MS/MS

The use of oxygen as a reaction gas for the removal of interferences in quadrupole ICP-MS is well established. However, prior to the development of the Agilent 8800 Triple Quadrupole ICP-MS (ICP-QQQ), the use of oxygen had been limited to determination of a small number of analytes in simple, well defined matrices. This is because oxygen can react with matrix components, analytes and polyatomic...

Practical Guide to ICP-MS

Quantification of Al2O3 nanoparticles in human cell lines applying inductively coupled plasma mass spectrometry (neb-ICP-MS, LA-ICP-MS) and flow cytometry-based methods

In order to quantify and compare the uptake of aluminum oxide nanoparticles of three different sizes into two human cell lines (skin keratinocytes (HaCaT) and lung epithelial cells (A549)), three analytical methods were applied: digestion followed by nebulization inductively coupled plasma mass spectrometry (neb-ICP-MS), direct laser ablation ICP-MS (LA-ICP-MS), and flow cytometry. Light and el...

Absolute quantification of transferrin in blood samples of harbour seals using HPLC-ICP-MS.

Harbour seals (Phoca vitulina) are bio-indicators for the assessment of their habitat and environmental changes. Besides population parameters and trends (survival, age structure, sex ratio), the individual health status represents a further important parameter for this assessment. The health status of seals is a complex and vague term, determined by a wide range of diagnostic parameters. Quant...

Multielemental composition of suet oil based on quantification by ultrawave/ICP-MS coupled with chemometric analysis.

Suet oil (SO) has been used commonly for food and medicine preparation. The determination of its elemental composition has became an important challenge for human safety and health owing to its possible contents of heavy metals or other elements. In this study, ultrawave single reaction chamber microwave digestion (Ultrawave) and inductively coupled plasma-mass spectrometry (ICP-MS) analysis wa...